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Rotem Rubinstein Laboratory
for Cell Recognition and Signaling

Publications

Modified Anti-PstS1 Bi-specific antibodies unlock potent protection against tuberculosis

PLOS Pathogens

On the same side: VISTA and its ligands interact in cis on the cell surface

Protein Science

Pathogenic variants affecting peptidyl arginine deiminase 3 and its major substrates underlie central centrifugal cicatricial alopecia

Journal of Investigative Dermatology

HMCN1 variants aggravate epidermolysis bullosa simplex phenotype

Journal of experimental medicine

Following the evolutionary paths of Dscam1 proteins toward highly specific homophilic interactions

Molecular Biology and Evolution

Clustered protocadherin cis-interactions are required for combinatorial cell–cell recognition underlying neuronal self-avoidance

Proceedings of the National Academy of Sciences

How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition

Elife

On the formation of ordered protein assemblies in cell–cell interfaces

Proceedings of the National Academy of Sciences

Chelicerata sDscam isoforms combine homophilic specificities to define unique cell recognition

Proceedings of the National Academy of Sciences

Mechanotransduction by PCDH15 relies on a novel cis-dimeric architecture

Neuron

Structural origins of clustered protocadherin-mediated neuronal barcoding

Seminars in cell & developmental biology

Protocadherin cis-dimer architecture and recognition unit diversity

Proceedings of the National Academy of Sciences

Structural, mutational and biophysical studies reveal a canonical mode of molecular recognition between immune receptor TIGIT and nectin-2

Molecular immunology

γ-Protocadherin structural diversity and functional implications

Elife

Structural basis of diverse homophilic recognition by clustered α-and β-protocadherins

Neuron

Molecular logic of neuronal self-recognition through protocadherin domain interactions

Cell

Single-cell identity generated by combinatorial homophilic interactions between α, β, and γ protocadherins

Cell

Functional classification of immune regulatory proteins

Structure

Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell–cell adhesion

Proceedings of the National Academy of Sciences

VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses

Journal of Experimental Medicine

Sequence, structure, function, immunity: structural genomics of costimulation

Immunological reviews

Predicting disulfide bond connectivity in proteins by correlated mutations analysis

Bioinformatics

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